UNESCO is one of the ten UNAIDS cosponsoring organizations.

• Office of the United Nations High Commissioner for Refugees (UNHCR)
• United Nations Children's Fund (UNICEF)
• World Food Programme (WFP)
• United Nations Development Programme (UNDP)
• United Nations Population Fund (UNFPA)
• United Nations Office on Drugs and Crime (UNODC)
• International Labour Organization (ILO)
• United Nations Educational, Scientific and Cultural Organization (UNESCO)
• World Health Organization (WHO)
• World Bank

The Cosponsors and the UNAIDS Secretariat comprise the Committee of Cosponsoring Organizations, which meets annually.

The UNAIDS Inter-Agency Task Team (IATT) on Education was created in 2002 to support accelerated and improved  responses by UNESCO's Education Sector to HIV and AIDS.